Which factor contributes to nonadherence in medication regimens?

• A. High out-of-pocket costs.
• B. Unlimited access to medications.
• C. Consistent pharmacy support.
• D. Clear, simple dosing schedules.

Answer: (A)

Financial barriers are a major driver of nonadherence. When patients must pay a large portion of medication costs, they may skip doses, cut pills in half, or not fill prescriptions to save money. This is especially common with chronic therapies that require ongoing, long-term use, where the cost adds up over time and the perceived benefit may feel distant.

Having unlimited access to medications would remove this barrier, making adherence more feasible. Consistent pharmacy support helps by organizing refills, providing reminders, and catching gaps before they occur. Clear, simple dosing schedules reduce confusion and forgetfulness, making it easier to take medications as prescribed.

Because cost is a concrete obstacle that directly affects a patient’s ability to obtain and take medications, high out-of-pocket costs are the factor most likely to contribute to nonadherence.